circRNA basic information
circBase ID: -
Name: hsa_circ_NEURL4
Synonym: circNEURL4
Host Gene: hsa-miR-1278
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: LATS1
Associated microRNA: hsa-miR-1278
Biological function: inhibit cell proliferation and invasion
Molecular mechanism: circNEURL4 may binding to hsa-miR-1278 and thus indirectly improving the expression of LATS1
Survival: better
Supported No.:
 1
Description:

circNEURL4 may probably serve as a diagnostic marker to predict PTC patients prognosis and a possible therapeutic target to PTC via miR-1278/LATS1 axis.
Other information
Title:

Circular RNA circNEURL4 inhibits cell proliferation and invasion of papillary thyroid carcinoma by sponging miR-1278 and regulating LATS1 expression.

Journal: Am J Transl Res
Published: 2021/7/27
PubMed ID: 34306334