circRNA basic information
circBase ID: -
Name: hsa_circ_TMC5
Synonym: CircTMC5
Host Gene: hsa-miR-361-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: RABL6
Associated microRNA: hsa-miR-361-3p
Biological function: circTMC5 overexpression promoted GC cell proliferation, invasion, and metastasis but inhibited apoptosis
Molecular mechanism: by sponging hsa-miR-361-3p and up-regulating RABL6
Survival: poor
Supported No.:
 1
Description:

CircTMC5 promotes GC and sponges miR-361-3p to up-regulate RABL6 expression, thus may have diagnostic and prognostic value in GC. RABL6 also displays therapeutic promise due to its role in the immune regulation of GC.
Other information
Title:

CircTMC5 promotes gastric cancer progression and metastasis by targeting miR-361-3p/RABL6.

Journal: Gastric Cancer
Published: 2021/7/24
PubMed ID: 34296378