circRNA basic information
circBase ID: hsa_circ_0000317
Name: -
Synonym: Circ_0000317
Host Gene: hsa-miR-520g
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HOXD10
Associated microRNA: hsa-miR-520g
Biological function: repressed CRC cell proliferation, migration, and invasion
Molecular mechanism: by targeting hsa-miR-520g and modulating HOXD10 expression
Survival: -
Supported No.:
 1
Description:

Functionally, circ_0000317 overexpression repressed CRC cell proliferation, migration, and invasion. Mechanistically, miR-520g was a direct target of circ_0000317 and miR-520g specifically modulated HOXD10 expression.
Other information
Title:

Circ_0000317/microRNA-520g/HOXD10 axis affects the biological characteristics of colorectal cancer.

Journal: Kaohsiung J Med Sci
Published: 2021/7/23
PubMed ID: 34292663