circRNA basic information
circBase ID: -
Name: hsa_circ_SETD3
Synonym: circSETD3
Host Gene: hsa-miR-641
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-641
Biological function: circSETD3 acted as a tumor suppressor to suppress BLCA cell proliferation, migration, EMT and stemness, and the underlying mechanisms had also been elucidated.
Molecular mechanism: circSETD3 sponged hsa-miR-641 to upregulate PTEN
Survival: better
Supported No.:
 1
Description:

circSETD3 acted as a vital tumor suppressor in BLCA via regulating the miR-641/PTEN axis.
Other information
Title:

Circular RNA circSETD3 hampers cell growth, migration, and stem cell properties in bladder cancer through sponging miR-641 to upregulate PTEN.

Journal: Cell Cycle
Published: 2021/7/22
PubMed ID: 34288821