circRNA basic information
circBase ID: hsa_circ_0082835
Name: -
Synonym: circRNA_0082835
Host Gene: hsa-miR-429
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: primary melanoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human melanoma cell lines (A375, WM451, SK-MEL-24, WM35), normal human melanocyte cell line (HM)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-429
Biological function: Inhibiting circ_0082835 and EZH2 suppressed the proliferation, invasion and migration, regulated the cell cycle levels, inhibited Wnt/beta-catenin and attenuated EMT in melanoma cells.
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circRNA_0082835 sponges miR-429 to affect the anti-tumor effect of miR-429 in primary melanoma and lymphatic metastasis.
Other information
Title:

Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429.

Journal: Bioengineered
Published: 2021/7/22
PubMed ID: 34288815