circRNA basic information
circBase ID: -
Name: hsa_circ_CCT3
Synonym: CircCCT3
Host Gene: hsa-miR-613
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGFA and VEGFR2
Associated microRNA: hsa-miR-613
Biological function: CircCCT3 promoted cell proliferation, migration, and invasion, and inhibited cell apoptosis in PC cells
Molecular mechanism: CircCCT3 acted as a sponge for the hsa-miR-613 to facilitate VEGFA and VEGFR2 expression
Survival: poor
Supported No.:
 1
Description:

Increased CircCCT3 suggests a poor prognosis for PC patients and promotes the migration and invasion through targeting VEGFA/VEGFR2 signaling. CircCCT3 may serve as a potential and promising therapeutic target for PC treatment.
Other information
Title:

CircCCT3 Acts as a Sponge of miR-613 to Promote Tumor Growth of Pancreatic Cancer Through Regulating VEGFA/VEGFR2 Signaling.

Journal: Balkan Med J
Published: 2021/7/19
PubMed ID: 34274912