circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1(e2)
Synonym: circFAT1(e2)
Host Gene: hsa-miR-30e-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCT116, RKO cell
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ITGA6
Associated microRNA: hsa-miR-30e-5p
Biological function: knockdown of miR-30e-5p enhanced CRC proliferation and migration via ITGA6
Molecular mechanism: circFAT1(e2) could sponge hsa-miR-30e-5p, which regulated the expression level of integrin alpha6 (ITGA6), the downstream target gene of hsa-miR-30e-5p
Survival: -
Supported No.:
 1
Description:

circFAT1(e2) could sponge miR-30e-5p, which regulated the expression level of integrin alpha6 (ITGA6), the downstream target gene of miR-30e-5p. Rescue assays demonstrated that knockdown of miR-30e-5p enhanced CRC proliferation and migration via ITGA6.
Other information
Title:

Circular RNA circFAT1(e2) Promotes Colorectal Cancer Tumorigenesis via the miR-30e-5p/ITGA6 Axis.

Journal: Comput Math Methods Med
Published: 2021/7/15
PubMed ID: 34257702