circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: circCCDC66
Host Gene: hsa-miR-320a, hsa-miR-320b
 
 
 
Disease basic information
DO ID:
0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXM1
Associated microRNA: hsa-miR-320a, hsa-miR-320b
Biological function: CircCCDC66 knockdown suppressed the proliferation, migration, and invasion of glioma cells
Molecular mechanism: circCCDC66 could sponge hsa-miR-320a, thereby increasing the expression of FOXM1
Survival: -
Supported No.:
1
Description:

CircCCDC66 could facilitate glioma cells proliferation, invasion and migration by down-regulating miR-320a and up-regulating FOXM1.

Other information
Title:

Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression.

Journal: Aging (Albany NY)
Published: 2021/7/13
PubMed ID: 34252882