circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_102541
Host Gene: hsa-miR-296-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PLK1
Associated microRNA: hsa-miR-296-5p
Biological function: knockdown of circRNA_102541 suppressed cell proliferation while promoted apoptosis of HUVEC cells
Molecular mechanism: via hsa-miR-296-5p/PLK1
Survival: -
Supported No.:
 1
Description:

circRNA_102541 was upregulated in atherosclerosis, and knockdown of circRNA_102541 suppressed cell proliferation while promoted apoptosis of HUVEC cells via miR-296-5p/PLK1. This novel pathway may serve essential roles on the development of atherosclerosis, and circRNA_102541 could be a.
Other information
Title:

Hsa_circRNA_102541 regulates the development of atherosclerosis by targeting miR-296-5p/PLK1 pathway.

Journal: Ir J Med Sci
Published: 2021/7/13
PubMed ID: 34251586