circRNA basic information
circBase ID: -
Name: hsa_circ_ARL15
Synonym: circARL15
Host Gene: hsa-miR-431-5p
 
 
 
Disease basic information
DO ID:
 90
DO name: degenerative disc disease
Disease details: Intervertebral disk degeneration
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
DN
Associated gene: DISC1
Associated microRNA: hsa-miR-431-5p
Biological function: circARL15 inhibited nucleus pulposus cell apoptosis but promoted nucleus pulposus cell proliferation
Molecular mechanism: by targeting the hsa-miR-431-5p/DISC1 signaling pathway
Survival: -
Supported No.:
 2
Description:

circARL15/miR-431-5p/DISC1 is involved in the pathogenesis of IDD, which might be helpful in determining the diagnostic biomarkers and providing potential therapeutic targets for patients with IDD.
Other information
Title:

circARL15 Plays a Critical Role in Intervertebral Disc Degeneration by Modulating miR-431-5p/DISC1.

Journal: Front Genet
Published: 2021/7/9
PubMed ID: 34234811