circRNA basic information
circBase ID: -
Name: hsa_circ_RAB3IP
Synonym: CircRAB3IP
Host Gene: hsa-miR-580-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TWIST1
Associated microRNA: hsa-miR-580-3p
Biological function: CircRAB3IP knockdown inhibited cell proliferation, migration, and invasion
Molecular mechanism: circRAB3IP directly binds to hsa-miR-580-3p.
Survival: poor
Supported No.:
 1
Description:

circRAB3IP acts as an oncogene in OS by regulating miR-580-3p/TWIST1 axis.
Other information
Title:

CircRAB3IP upregulates twist family BHLH transcription factor (TWIST1) to promote osteosarcoma progression by sponging miR-580-3p.

Journal: Bioengineered
Published: 2021/7/6
PubMed ID: 34224315