circRNA basic information
circBase ID: -
Name: hsa_circ_RASSF2
Synonym: CircRASSF2
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXA1
Associated microRNA: hsa-miR-1205
Biological function: an overt decrease was detected in the proliferation, clone formation ability, migration and invasion of breast cancer cells in cells when circRASSF2 was knocked down
Molecular mechanism: over-expression of hsa-miR-1205 decreased HOXA1 protein expression, and HOXA1 protein expression decreased when circRASSF2 were knocked down
Survival: poor
Supported No.:
 1
Description:

over-expression of miR-1205 decreased HOXA1 protein expression, and HOXA1 protein expression decreased when circRASSF2 were knocked down, and when miR-1205 expression was inhibited, HOXA1 expression was significantly increased.
Other information
Title:

CircRASSF2 acts as a prognostic factor and promotes breast cancer progression by modulating miR-1205/HOXA1 axis.

Journal: Bioengineered
Published: 2021/6/29
PubMed ID: 34180753