circRNA basic information
circBase ID: -
Name: hsa_circ_SLIT2
Synonym: circSLIT2
Host Gene: hsa-miR-510-5p
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human pancreatic ductal epithelial cell line (HPDE6), PDAC cells (PANC-1, Capan-2, SW1990, BxPC-3)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Myc/LDHA
Associated microRNA: hsa-miR-510-5p
Biological function: circSLIT2 promoted the aerobic glycolysis and proliferation of PDAC cells in vitro, and circSLIT2 knockdown inhibited tumor growth in vivo
Molecular mechanism: circSLIT2 acted as miRNA sponge to target hsa-miR-510-5p/c-Myc axis
Survival: -
Supported No.:
 1
Description:

Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis.
Other information
Title:

Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis.

Journal: Cell Death Dis
Published: 2021/6/26
PubMed ID: 34168116