circRNA basic information
circBase ID: -
Name: hsa_circ_ASXL1
Synonym: CircASXL1
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GRIK3
Associated microRNA: hsa-miR-1205
Biological function: CircASXL1 knockdown inhibited cell colony-forming ability, migration and invasion, whereas induced cell arrest at G0/G1 phase and cell apoptosis in CRC cells
Molecular mechanism: circASXL1 silencing hindered tumor formation by upregulating hsa-miR-1205 and downregulating GRIK3 expression
Survival: -
Supported No.:
 1
Description:

CircASXL1 acted an oncogenic role in CRC malignant progression via inducing GRIK3 through sponging miR-1205.
Other information
Title:

CircASXL1 knockdown represses the progression of colorectal cancer by downregulating GRIK3 expression by sponging miR-1205.

Journal: World J Surg Oncol
Published: 2021/6/16
PubMed ID: 34127015