circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO3
Synonym: circFOXO3
Host Gene: hsa-miR-214
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: KDM2A
Associated microRNA: hsa-miR-214
Biological function: knockdown of circFOXO3 prevents the invasion and proliferation of oral cancer cells
Molecular mechanism: circFOXO3 sponges hsa-miR-214 to up-regulate the expression of KDM2A
Survival: -
Supported No.:
 1
Description:

circFOXO3 sponges miR-214 to up-regulate the expression of KDM2A, thus promotes tumor progression in OSCC.
Other information
Title:

Circular RNA circFOXO3 regulates KDM2A by targeting miR-214 to promote tumor growth and metastasis in oral squamous cell carcinoma.

Journal: J Cell Mol Med
Published: 2021/6/13
PubMed ID: 34117688