circRNA basic information
circBase ID: -
Name: hsa_circ_NALCN
Synonym: CircNALCN
Host Gene: hsa-miR-493-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-493-3p
Biological function: the overexpression of circNALCN significantly inhibited the proliferation and migration of glioma cells
Molecular mechanism: hsa-miR-493-3p/PTEN axis
Survival: poor
Supported No.:
 1
Description:

circNALCN acted as a competing endogenous RNA for miR-493-3p to relieve the repressive effects of miR-493-3p on its target, PTEN, suppressing glioma tumorigenesis.
Other information
Title:

CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression.

Journal: Cancer Cell Int
Published: 2021/6/12
PubMed ID: 34112159