circRNA basic information
circBase ID: -
Name: hsa_circ_FAM158A
Synonym: circ-FAM158A
Host Gene: hsa-miR-138-5p
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: SLC7A5
Associated microRNA: hsa-miR-138-5p
Biological function: Circ-FAM158A knockdown inhibited RB cell proliferation, metastasis, and promoted apoptosis in vitro and in vivo
Molecular mechanism: circ-FAM158A positively regulated SLC7A5 expression by sponging hsa-miR-138-5p
Survival: -
Supported No.:
 3
Description:

Circ-FAM158A knockdown inhibited the progression of RB by regulating miR-138-5p/SLC7A5 axis, which provided new insights into the pathogenesis of RB.
Other information
Title:

Circular RNA circ-FAM158A promotes retinoblastoma progression by regulating miR-138-5p/SLC7A5 axis.

Journal: Exp Eye Res
Published: 2021/6/9
PubMed ID: 34102206