circRNA basic information
circBase ID: hsa_circ_0032463
Name: hsa_circ_SIPA1L1
Synonym: -
Host Gene: hsa-miR-498
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LEF1
Associated microRNA: hsa-miR-498
Biological function: promoted the migration and proliferation abilities of OS cells and suppressed the apoptosis ability of OS cells
Molecular mechanism: by binding to hsa-miR-498 and inhibiting LEF1 expression
Survival: -
Supported No.:
 3
Description:

by binding to miR-498 and inhibiting LEF1 expression, circ_0032463 promoted the migration and proliferation abilities of OS cells and suppressed the apoptosis ability of OS cells.
Other information
Title:

Circular RNA hsa_circ_0032463 Acts as the Tumor Promoter in Osteosarcoma by Regulating the MicroRNA 498/LEF1 Axis.

Journal: Mol Cell Biol
Published: 2021/6/8
PubMed ID: 34096776