circRNA basic information
circBase ID: hsa_circ_0084615
Name: -
Synonym: Circ_0084615
Host Gene: hsa-miR-599
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human normal colonic mucosal cell line (FHC), human CRC cell lines (HCT116, SW480, DLD1, RKO cells)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: DNMT3A
Associated microRNA: hsa-miR-599
Biological function: depletion of circ_0084615 impeded CRC cell proliferation, migration and invasion
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

Circ_0084615 is a tumor-promoting circRNA in CRC that functions as a competing endogenous RNA to regulate DNMT3A expression via sponging miR-599.
Other information
Title:

Circ_0084615 is an oncogenic circular RNA in colorectal cancer and promotes DNMT3A expression via repressing miR-599.

Journal: Pathol Res Pract
Published: 2021/6/7
PubMed ID: 34091391