circRNA basic information
circBase ID: -
Name: hsa_circ_ACAP2
Synonym: Circ-ACAP2
Host Gene: hsa-miR-143-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (HCT-116, DLD1, SW620, SW480), normal human colorectal epithelial cell line (HIEC6)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FZD4
Associated microRNA: hsa-miR-143-3p
Biological function: Circ-ACAP2 facilitated the proliferation, migration, invasion and radioresistance whereas inhibited the apoptosis of CRC cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ-ACAP2 contributed to the development and radioresistance of CRC partly through targeting miR-143-3p/FZD4 axis, which provided novel potential diagnostic and therapeutic targets for CRC.
Other information
Title:

Circ-ACAP2 facilitates the progression of colorectal cancer through mediating miR-143-3p/FZD4 axis.

Journal: Eur J Clin Invest
Published: 2021/6/5
PubMed ID: 34085707