circRNA basic information
circBase ID: hsa_circ_0102049
Name: -
Synonym: circ_0102049
Host Gene: hsa-miR-520g-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: MG63 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: PLK2
Associated microRNA: hsa-miR-520g-3p
Biological function: the silence of circ_0102049 could markedly promote the proliferation, invasion, migration and cell-cycle promotion while inhibiting the apoptosis of OS cell line MG63 cells in vitro
Molecular mechanism: through regulating hsa-miR-520g-3p/PLK2 axis
Survival: -
Supported No.:
 2
Description:

circ_0102049 suppressed the progression of osteosarcoma via modulating miR-520g-3p/PLK2/TAp73 axis, providing a potential therapeutic target for OS.
Other information
Title:

Circular RNA 0102049 suppresses the progression of osteosarcoma through modulating miR-520g-3p/PLK2 axis.

Journal: Bioengineered
Published: 2021/6/2
PubMed ID: 34060415