circRNA basic information
circBase ID: hsa_circ_0006677
Name: hsa_circ_WDR78
Synonym: -
Host Gene: hsa-miR-578
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (CALU3, CALU6, A549, H1229, H1975), human bronchial epithelial cells (HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOSC2
Associated microRNA: hsa-miR-578
Biological function: Overexpression of circ_0006677 significantly inhibited the ability of NSCLC cell proliferation, migration, invasion, and glycolysis
Molecular mechanism: regulating the expression of the signal transducer inhibitor SOSC2 through sponging microRNA-578 (hsa-miR-578)
Survival: better
Supported No.:
 2
Description:

circ_0006677 could inhibit NSCLC progression and glycolysis by regulating the expression of the signal transducer inhibitor SOSC2 through sponging microRNA-578 (miR-578).
Other information
Title:

CircRNA circ_0006677 Inhibits the Progression and Glycolysis in Non-Small-Cell Lung Cancer by Sponging miR-578 and Regulating SOCS2 Expression.

Journal: Front Pharmacol
Published: 2021/6/1
PubMed ID: 34054537