circRNA basic information
circBase ID: -
Name: hsa_circ_ANKRD36
Synonym: circANKRD36
Host Gene: hsa-miR-330
 
 
 
Disease basic information
DO ID:
 850
DO name: lung disease
Disease details: Acute lung injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RAW264.7 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ROCK1
Associated microRNA: hsa-miR-330
Biological function: Knockdown of circANKRD36 inhibited cell viability and migration and alleviated inflammation of lipopolysaccharide-stimulated (LPS-stimulated) RAW264.7 cells.
Molecular mechanism: circANKRD36 serves as a sponge for miR-330 and ROCK1 was directly targeted by miR-330.
Survival: -
Supported No.:
 1
Description:

In short, circANKRD36 knockdown suppressed cell viability and migration of LPS-stimulated RAW264.7 cells in vitro via sponging miR-330, which may provide new ideas for the treatment of sepsis-induced ARDS.
Other information
Title:

CircANKRD36 Knockdown Suppressed Cell Viability and Migration of LPS-Stimulated RAW264.7 Cells by Sponging MiR-330.

Journal: Inflammation
Published: 2021/5/28
PubMed ID: 34041646