circRNA basic information
circBase ID: -
Name: hsa_circ_WDR27
Synonym: circWDR27
Host Gene: hsa-miR-215-5p
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human thyroid follicular epithelial cells (Nthy-ori3-1), human PTC cells (TPC-1, IHH-4)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIM44
Associated microRNA: hsa-miR-215-5p
Biological function: Knockdown of circWDR27 suppressed cell proliferation and metastasis and induced cell cycle arrest and apoptosis in PTC cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

CircWDR27 accelerates PTC progression via regulating miR-215-5p/TRIM44 axis, providing a potential therapeutic target for PTC.
Other information
Title:

Circular RNA circWDR27 Promotes Papillary Thyroid Cancer Progression by Regulating miR-215-5p/TRIM44 Axis.

Journal: Onco Targets Ther
Published: 2021/5/28
PubMed ID: 34040392