circRNA basic information
circBase ID: hsa_circ_0045714
Name: hsa_circ_UNK
Synonym: -
Host Gene: hsa-miR-193b
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: IGF1R
Associated microRNA: hsa-miR-193b
Biological function: upregulate chondrocyte proliferation
Molecular mechanism: regulate extracellular matrix synthesis as well as proliferation and apoptosis of chondrocytes by promoting the expression of hsa-miR-193b target gene IGF1R
Survival: -
Supported No.:
 4
Description:

hsa_circ_0045714 can regulate extracellular matrix synthesis as well as proliferation and apoptosis of chondrocytes by promoting the expression of miR-193b target gene IGF1R. The findings will provide new proofs for studies on the applications of circRNA in OA and other orthopedic diseases.
Other information
Title:

Hsa_circ_0045714 regulates chondrocyte proliferation, apoptosis and extracellular matrix synthesis by promoting the expression of miR-193b target gene IGF1R.

Journal: Hum Cell
Published: 2017/8/11
PubMed ID: 28795385