circRNA basic information
circBase ID: -
Name: hsa_circ_ABCB10
Synonym: circABCB10
Host Gene: hsa-miR-588
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AMC-HN-8, Hep-2 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: CXCR4
Associated microRNA: hsa-miR-588
Biological function: the depletion of circABCB10 significantly inhibited the proliferation and induced the apoptosis
Molecular mechanism: by regulating hsa-miR-588/CXCR4 axis
Survival: -
Supported No.:
 1
Description:

circABCB10 was involved in the malignant progression of LSCC by regulating miR-588/CXCR4 axis.
Other information
Title:

Circular RNA ABCB10 contributes to laryngeal squamous cell carcinoma (LSCC) progression by modulating the miR-588/CXCR4 axis.

Journal: Aging (Albany NY)
Published: 2021/5/21
PubMed ID: 34015764