circRNA basic information
circBase ID: -
Name: hsa_circ_CORO1C
Synonym: -
Host Gene: hsa-miR-138-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal gastric epithelial cell line (GES-1), GC cell lines (HGC27, AGS, MKN45)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF12
Associated microRNA: hsa-miR-138-5p
Biological function: Circ_CORO1C knockdown suppressed colony formation ability, viability, migration, invasion and EMT in GC cells, while promoted cell apoptosis in vitro
Molecular mechanism: regulating hsa-miR-138-5p/KLF12 axis
Survival: -
Supported No.:
 2
Description:

Depletion of circ_CORO1C suppressed GC progression by regulating miR-138-5p/KLF12 axis, offering a potential molecular target for GC therapy.
Other information
Title:

Depletion of Circular RNA circ_CORO1C Suppresses Gastric Cancer Development by Modulating miR-138-5p/KLF12 Axis.

Journal: Cancer Manag Res
Published: 2021/5/20
PubMed ID: 34007212