circRNA basic information
circBase ID: -
Name: hsa_circ_AMD1
Synonym: circAMD1
Host Gene: hsa-miR-27a-3p
 
 
 
Disease basic information
DO ID:
 37
DO name: skin disease
Disease details: skin
Species: human
Species details: human
Sample type: cell line
Sample type details: human dermal fibroblasts
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-27a-3p
Biological function: overexpressing circAMD1 rescued the functional and phenotypic alterations of p63-mutant HDFs
Molecular mechanism: miR-27a-3p was circAMD1 target involved in effects of circAMD1 in P63-mutant HDFs.
Survival: -
Supported No.:
 1
Description:

Collectively, our data show that circAMD1 functions as a miR-27a-3p sponge that inhibits the functional and phenotypical alteration of P63-mutant HDFs and may be a critical marker in pathogenesis regarding P63-associated traits.
Other information
Title:

CircAMD1 regulates proliferation and collagen synthesis via sponging miR-27a-3p in P63-mutant human dermal fibroblasts.

Journal: Differentiation
Published: 2021/5/16
PubMed ID: 33991897