circRNA basic information
circBase ID: -
Name: hsa_circ_POLA2
Synonym: -
Host Gene: hsa-miR-34a
 
 
 
Disease basic information
DO ID:
9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bone marrow stromal cells (HS-5), human AML cell lines (Kasumi-6, Kasumi-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-34a
Biological function: promotes cell proliferation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

Circ_POLA2 is upregulated in AML and promotes cell proliferation by suppressing the production of mature miR-34a.

Other information
Title:

CircRNA circ_POLA2 is Upregulated in Acute Myeloid Leukemia (AML) and Promotes Cell Proliferation by Suppressing the Production of Mature miR-34a.

Journal: Cancer Manag Res
Published: 2021/5/14
PubMed ID: 33981162