circRNA basic information
circBase ID: -
Name: -
Synonym: circ_001839
Host Gene: hsa-miR-432-3p
 
 
 
Disease basic information
DO ID:
 326
DO name: ischemia
Disease details: renal ischemia-reperfusion injury
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: NRK52E cells.
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NLRP3
Associated microRNA: hsa-miR-432-3p
Biological function: Circ 001839 overexpression significantly increased inflammation through promoting TNF-¦Á, IFN-gamma, and IL-6 expression levels in NRK52E cells.
Molecular mechanism: Overexpression of miR-432-3p significantly promoted inflammation in NRK52E cells via induction of NLRP3
Survival: -
Supported No.:
 1
Description:

These findings suggested that circ 001839 promoted inflammation in RI-RI through NLRP3 by miR-432-3p.
Other information
Title:

Hsa Circ 001839 Promoted Inflammation in Renal Ischemia-Reperfusion Injury Through NLRP3 by miR-432-3p.

Journal: Nephron
Published: 2021/5/12
PubMed ID: 33975327