circRNA basic information
circBase ID: hsa_circ_0009910
Name: -
Synonym: Circ_0009910
Host Gene: hsa-miR-5195-3p
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: cell line
Sample type details: HL-60, MOLM-13 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GRB10
Associated microRNA: hsa-miR-5195-3p
Biological function: blocking circ_0009910 via small interfering RNA (siRNA) suppressed cell proliferation and cell cycle progression, but facilitated apoptosis rate of HL-60 and MOLM-13 cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

circ_0009910-containing exosomes mediated proliferation, apoptosis and cell cycle progression of AML cells partially through miR-5195-3p/GRB10 axis.
Other information
Title:

Circ_0009910 shuttled by exosomes regulates proliferation, cell cycle and apoptosis of acute myeloid leukemia cells by regulating miR-5195-3p/GRB10 axis.

Journal: Hematol Oncol
Published: 2021/5/11
PubMed ID: 33969901