circRNA basic information
circBase ID: -
Name: hsa_circ_ASH2L
Synonym: CircASH2L
Host Gene: hsa-miR-129-5p
 
 
 
Disease basic information
DO ID:
 7148
DO name: rheumatoid arthritis
Disease details: rheumatoid arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RAFLSs, normal FLSs (N-FLSs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HIPK2
Associated microRNA: hsa-miR-129-5p
Biological function: CircASH2L knockdown in RA-FLSs suppressed cell proliferative, migratory, and invasive capacities, triggered cell cycle arrest, promoted apoptosis, and inhibited inflammation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

CircASH2L promoted RA-FLS growth, motility, and inflammation through miR-129-5p/HIPK2 axis.
Other information
Title:

CircASH2L facilitates tumor-like biologic behaviours and inflammation of fibroblast-like synoviocytes via miR-129-5p/HIPK2 axis in rheumatoid arthritis.

Journal: J Orthop Surg Res
Published: 2021/5/10
PubMed ID: 33964939