circRNA basic information
circBase ID: hsa_circ_0006401
Name: hsa_circ_col6a3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CRC cell lines (SW480, SW620)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promoted CRC proliferation and migration
Molecular mechanism: Hsa_circ_0006401 peptides decreased the mRNA and protein level of the host gene col6a3 by promoting col6a3 mRNA stabilation
Survival: poor
Supported No.:
 1
Description:

circRNAs generated from col6a3 that contain an open-reading frame (ORF) encode a novel 198-aa functional peptide and hsa_circ_0006401 peptides promote stability of the host gene col6a3 mRNA to promote CRC proliferation and metastasis.
Other information
Title:

Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma.

Journal: Cell Death Dis
Published: 2021/5/6
PubMed ID: 33947841