circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: CircRNA ZNF609
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human umbilical vein endothelial cells (HUVECs), NPC cell lines (CNE1, HNE1, 5-8F, C666-1, HONE-1), a human normal nasopharyngeal epithelial cell line (NP69)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STMN1
Associated microRNA: hsa-miR-145
Biological function: Silencing circ-ZNF609 suppressed cell proliferation, migration, and angiogenesis in NPC, while knockdown of miR-145 reversed these effects
Molecular mechanism: upregulating the expression of STMN1 by sponging hsa-miR-145
Survival: -
Supported No.:
 5
Description:

circ-ZNF609 promotes cell proliferation, migration, and angiogenesis in NPC by upregulating the expression of STMN1 by sponging miR-145 in NPC.
Other information
Title:

CircRNA ZNF609 promotes angiogenesis in nasopharyngeal carcinoma by regulating miR-145/STMN1 axis.

Journal: Kaohsiung J Med Sci
Published: 2021/5/5
PubMed ID: 33943007