circRNA basic information
circBase ID: hsa_circ_0078607
Name: hsa_circ_SLC22A3
Synonym: -
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MKN-28 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAP1B
Associated microRNA: hsa-miR-188-3p
Biological function: Knockdown of circ_0078607 could prevent proliferation and induce cell apoptosis in MKN-28 cells
Molecular mechanism: Silencing of circ_0078607 inhibited ERK1/2/AKT signal pathways via regulating hsa-miR-188-3p/RAP1B
Survival: -
Supported No.:
 1
Description:

Knockdown of circ_0078607 inhibits the proliferation and induces apoptosis of gastric cancer via miR-188-3p/RAP1B signal pathway.
Other information
Title:

Silencing of circ_0078607 prevents development of gastric cancer and inactivates the ERK1/2/AKT pathway through the miR-188-3p/RAP1B axis.

Journal: Anticancer Drugs
Published: 2021/5/1
PubMed ID: 33929989