circRNA basic information
circBase ID: hsa_circ_0000117
Name: hsa_circ_MAN1A2
Synonym: -
Host Gene: hsa-miR-337-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human immortalized gastric epithelial cell line (GES-1), GC cell lines (AGS, HGC-27, SGC7901, BGC823, SNU-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STAT3
Associated microRNA: hsa-miR-337-3p
Biological function: Depleted hsa_circ_0000117 decreased GC proliferation and invasion
Molecular mechanism: hsa_circ_0000117/hsa-miR-337-3p/STAT3 axis
Survival: -
Supported No.:
 2
Description:

hsa_circ_0000117 exhibited oncogene properties in combination with the hsa_circ_0000117/miR-337-3p/STAT3 axis in GC, potentially providing a new therapeutic target for GC.
Other information
Title:

Circular RNA hsa_circ_0000117 accelerates the proliferation and invasion of gastric cancer cells by regulating the microRNA-337-3p/signal transducer and activator of transcription 3 axis.

Journal: Bioengineered
Published: 2021/4/27
PubMed ID: 33896365