circRNA basic information
circBase ID: -
Name: hsa_circ_E2F2
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: OVCAR-3, SKOV3, A2780, CAOV3, IGROV1, ES2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F2
Associated microRNA: -
Biological function: The knockdown of circE2F2 in OC cells suppressed cell proliferation, migration, invasion, and cellular glucose metabolism
Molecular mechanism: by upregulating the expression of E2F2 protein via binding to HuR protein
Survival: -
Supported No.:
 1
Description:

circE2F2 promoted OC cell proliferation, metastasis, and glucose metabolism by stabilizing the E2F2 mRNA via binding to the HuR protein.
Other information
Title:

Circular RNA circE2F2 promotes malignant progression of ovarian cancer cells by upregulating the expression of E2F2 protein via binding to HuR protein.

Journal: Cell Signal
Published: 2021/4/25
PubMed ID: 33894314