circRNA basic information
circBase ID: hsa_circ_0004104
Name: -
Synonym: circ_0004104
Host Gene: hsa-miR-328-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIM14
Associated microRNA: hsa-miR-328-3p
Biological function: ox-LDL exposure suppressed cell viability and angiogenic ability whereas promoted the apoptosis, inflammation and oxidative stress of HUVECs partly through up-regulating circ_0004104.
Molecular mechanism: _icroRNA-328-3p (miR-328-3p) was confirmed as a target of circ_0004104.
Survival: -
Supported No.:
 2
Description:

Circ_0004104 knockdown attenuated ox-LDL-induced dysfunction in HUVECs via miR-328-3p-mediated regulation of TRIM14.
Other information
Title:

Circ_0004104 knockdown alleviates oxidized low-density lipoprotein-induced dysfunction in vascular endothelial cells through targeting miR-328-3p/TRIM14 axis in atherosclerosis.

Journal: BMC Cardiovasc Disord
Published: 2021/4/25
PubMed ID: 33892646