circRNA basic information
circBase ID: -
Name: hsa_circ_FBXW7
Synonym: -
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BEAS-2B, A549, HCC2279, H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: BARX2
Associated microRNA: hsa-miR-942-5p
Biological function: circFBXW7 overexpression inhibited proliferation and migration
Molecular mechanism: circFBXW7 target miRNA-942-5p which regulates the EMT gene BARX2
Survival: better
Supported No.:
 1
Description:

circFBXW7 inhibits proliferation and migration by controlling the miR-942-5p/BARX2 axis in LUAD cell lines and its levels correlates with patient survival suggesting that regulating circFBXW7 could have therapeutic value in treating LUAD patients.
Other information
Title:

circFBXW7 attenuates malignant progression in lung adenocarcinoma by sponging miR-942-5p.

Journal: Transl Lung Cancer Res
Published: 2021/4/24
PubMed ID: 33889522