circRNA basic information
circBase ID: hsa_circ_0006168
Name: -
Synonym: circ_0006168
Host Gene: hsa-miR-516b-5p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Eca109, KYSE150, KYSE180, KYSE450
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: XBP1
Associated microRNA: hsa-miR-516b-5p
Biological function: The interference of circ_0006168 restrained the motility and proliferation of ESCC cells
Molecular mechanism: Circ_0006168 acted as hsa-miR-516b-5p sponge to up-regulate XBP1 expression in ESCC cells
Survival: -
Supported No.:
 3
Description:

circ_0006168 contributed to ESCC development through promoting the proliferation and motility of ESCC cells via mediating miR-516b-5p/XBP1 axis.
Other information
Title:

Circ_0006168 Promotes the Migration, Invasion and Proliferation of Esophageal Squamous Cell Carcinoma Cells via miR-516b-5p-Dependent Regulation of XBP1.

Journal: Onco Targets Ther
Published: 2021/4/23
PubMed ID: 33883902