circRNA basic information
circBase ID: hsa_circ_0055625
Name: -
Synonym: Circ_0055625
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SW620, SW480
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MSI1
Associated microRNA: hsa-miR-338-3p
Biological function: Circ_0055625 knockdown or MSI1 silencing repressed cell proliferation, migration, and invasion and promoted cell apoptosis and radiosensitivity in colon cancer
Molecular mechanism: circ_0055625 acted as a sponge for hsa-miR-338-3p to regulate MSI1
Survival: -
Supported No.:
 2
Description:

Circ_0055625 repression inhibited the progression and radioresistance of colon cancer by downregulating MSI1 through sponging miR-338-3p. This result might provide a theoretical basis for improving the therapy of colon cancer with radiation.
Other information
Title:

Circ_0055625 knockdown inhibits tumorigenesis and improves radiosensitivity by regulating miR-338-3p/MSI1 axis in colon cancer.

Journal: World J Surg Oncol
Published: 2021/4/23
PubMed ID: 33882945