circRNA basic information
circBase ID: hsa_circ_0003204
Name: -
Synonym: circ_0003204
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: Atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HDAC9
Associated microRNA: hsa-miR-942-5p
Biological function: Silencing of circ_0003204 enhanced cell viability and inhibited cell apoptosis, oxidative stress and inflammation in ox-LDL-disposed HUVECs.
Molecular mechanism: circ_0003204 targeted miR-942-5p to regulate ox-LDL-resulted HUVECs injury.
Survival: -
Supported No.:
 7
Description:

Circ_0003204 aggravated ox-LDL-induced HUVECs damage via modulating miR-942-5p/HDAC9 pathway.
Other information
Title:

circ_0003204 Regulates Cell Growth, Oxidative Stress, and Inflammation in ox-LDL-Induced Vascular Endothelial Cells via Regulating miR-942-5p/HDAC9 Axis.

Journal: Front Cardiovasc Med
Published: 2021/4/20
PubMed ID: 33869307