circRNA basic information
circBase ID: hsa_circ_0003288
Name: hsa_circ_BIRC6
Synonym: -
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: HepG2, Huh7, SMMC-7721, Bel-7402
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PD-L1
Associated microRNA: hsa-miR-145
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

hsa_circ_0003288 promoted EMT and invasion of HCC via the hsa_circ_0003288/miR-145/PD-L1 axis through the PI3K/Akt pathway. Targeting hsa_circ_0003288 may be a therapeutic strategy for the treatment of HCC.
Other information
Title:

Circular RNA hsa_circ_0003288 induces EMT and invasion by regulating hsa_circ_0003288/miR-145/PD-L1 axis in hepatocellular carcinoma.

Journal: Cancer Cell Int
Published: 2021/4/17
PubMed ID: 33858418