circRNA basic information
circBase ID: hsa_circ_000881
Name: -
Synonym: hsa-circ-000881
Host Gene: hsa-miR-665
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, HCC827, H23, H1975, H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PRICKLE2
Associated microRNA: hsa-miR-665
Biological function: Overexpression of circ-000881 attenuated cell growth, migration, and invasion, whereas its knockdown enhanced the malignancy of LUAD cells
Molecular mechanism: via a hsa-miR-665/PRICKLE2 axis
Survival: -
Supported No.:
 1
Description:

Circ-000881 has inhibitory effects on LUAD via a miR-665/PRICKLE2 axis, suggesting that circ-000881 may be an underlying therapeutic target for LUAD.
Other information
Title:

Circular RNA hsa-circ-000881 suppresses the progression of lung adenocarcinoma in vitro via a miR-665/PRICKLE2 axis.

Journal: Ann Transl Med
Published: 2021/4/15
PubMed ID: 33850895