circRNA basic information
circBase ID: -
Name: mmu_circ_HECTD1
Synonym: -
Host Gene: mmu-miR-27a-3p
 
 
 
Disease basic information
DO ID:
 3526
DO name: cerebral infarction
Disease details: cerebral infarction
Species: mouse
Species details: mouse
Sample type: tissue, cell line
Sample type details: HT22
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FSTL1
Associated microRNA: mmu-miR-27a-3p
Biological function: circ_HECTD1 knockdown could boost cell proliferative ability and repress apoptosis in OGD/R-triggered HT22 cells in vitro
Molecular mechanism: regulate FSTL1 expression by sponging mmu-miR-27a-3p
Survival: -
Supported No.:
 1
Description:

Circ_HECTD1 deficiency could mitigate OGD/R-induced HT22 cell damage by modulating the miR-27a-3p/FSTL1 axis, providing a promising therapeutic target for cerebral infarction treatment.
Other information
Title:

Circular RNA circ_HECTD1 regulates cell injury after cerebral infarction by miR-27a-3p/FSTL1 axis.

Journal: Cell Cycle
Published: 2021/4/13
PubMed ID: 33843447