circRNA basic information
circBase ID: hsa_circ_0092314
Name: -
Synonym: circ_0092314
Host Gene: hsa-miR-671
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AsPC-1, BxPC-3, SW-1990, PaCa-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: S100P
Associated microRNA: hsa-miR-671
Biological function: promotes proliferation, invasion and EMT in vitro and tumor growth in vivo
Molecular mechanism: circ_0092314 directly binds to hsa-miR-671 and relieve its suppression of the downstream target S100P, which induces EMT and activates the AKT signaling pathway
Survival: poor
Supported No.:
 1
Description:

circ_0092314 exerts critical roles in promoting the EMT features of PAAD cells, and provides insight into how elevated expression of circ_0092314 might influence PAAD progression.
Other information
Title:

CircRNA circ_0092314 Induces Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells via Elevating the Expression of S100P by Sponging miR-671.

Journal: Front Oncol
Published: 2021/4/13
PubMed ID: 33842379