circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: -
Host Gene: hsa-miR-211-5p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Nthy-ori 3-1, CAL62, TPC1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PDK4
Associated microRNA: hsa-miR-211-5p
Biological function: silencing circCCDC66 inhibited TC cell proliferation, migratory and invasive abilities and glycolysis in vitro.
Molecular mechanism: by sponging hsa-miR-211-5p and increasing expression of PDK4
Survival: -
Supported No.:
 1
Description:

circCCDC66 could promote TC cell proliferation, migratory and invasive abilities and invasion and glycolysis through the miR-211-5p/PDK4 axis.
Other information
Title:

circCCDC66 promotes thyroid cancer cell proliferation, migratory and invasive abilities and glycolysis through the miR-211-5p/PDK4 axis.

Journal: Oncol Lett
Published: 2021/4/13
PubMed ID: 33841577