circRNA basic information
circBase ID: -
Name: hsa_circ_MBOAT2
Synonym: -
Host Gene: hsa-miR-433-3p
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: AsPC-1, BxPC-3, PANC-1, SW1990
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GOT1
Associated microRNA: hsa-miR-433-3p
Biological function: Circ-MBOAT2 silencing repressed cell proliferation, migration, invasion and glutamine catabolism, whereas promoted cell apoptosis in pancreatic cancer
Molecular mechanism: acted as a sponge of hsa-miR-433-3p, which was found to be associate with GOT1
Survival: -
Supported No.:
 2
Description:

Circ-MBOAT2 modulated tumor development and glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer. This finding suggests that circ-MBOAT2 may be a therapeutic target for pancreatic cancer.
Other information
Title:

Circ-MBOAT2 knockdown represses tumor progression and glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer.

Journal: J Exp Clin Cancer Res
Published: 2021/4/10
PubMed ID: 33832516