circRNA basic information
circBase ID: hsa_circ_0032463
Name: hsa_circ_SIPA1L1
Synonym: -
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HOS, U2OS, Saos-2, SOSP-9607
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PNN
Associated microRNA: hsa-miR-330-3p
Biological function: facilitated cell proliferation, viability, invasion and adhesion, but attenuated cell apoptosis
Molecular mechanism: inhibited miR_330_3p to upregulate PNN expression
Survival: -
Supported No.:
 3
Description:

this study confirmed that by regulating the miR_330_3p/PNN axis, circular RNA circ_0032463 could function as a tumor enhancer in cells with OS.
Other information
Title:

Hsa_circ_0032463 acts as the tumor promoter in osteosarcoma by regulating the miR_330_3p/PNN axis.

Journal: Int J Mol Med
Published: 2021/4/1
PubMed ID: 33786605