circRNA basic information
circBase ID: -
Name: hsa_circ_ASPH
Synonym: -
Host Gene: hsa-miR-599
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U251, U87MG
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: AR/SOCS2-AS1 signaling
Associated microRNA: hsa-miR-599
Biological function: circ-ASPH increased cell proliferation, migration and invasion in GM cells
Molecular mechanism: circ-ASPH counteracted microRNA (miR)-599-mediated androgen receptor (AR) suppression by acting as a sponge for hsa-miR-599
Survival: poor
Supported No.:
 1
Description:

circ-ASPH/miR-599/AR/SOCS2-AS1 signaling may be a promising biomarker/therapeutic target for GM.
Other information
Title:

Upregulation of circ-ASPH contributes to glioma cell proliferation and aggressiveness by targeting the miR-599/AR/SOCS2-AS1 signaling pathway.

Journal: Oncol Lett
Published: 2021/3/30
PubMed ID: 33777211